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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-1-28
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pubmed:abstractText |
Fecal incontinence is a common disorder that can have devastating social and psychologic consequences. However, there are no long-term ideal solutions for such patients. Although loss of continence is multifactorial, the integrity of the internal anal sphincter (IAS) has particular significance. We previously described the development of 3-dimensional bioengineered constructs using isolated smooth muscle tissue from donor C57BL/6 IAS. We hypothesized that the bioengineered ring constructs would retain cellular viability and promote neovascularization upon implantation into a recipient mouse.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-10686198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-10937836,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-11000388,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-11082363,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-11326237,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-11805574,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-11861428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-11889066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-11990524,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-12099717,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-12479248,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-15043291,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-15468796,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-15738680,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-16253976,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-16266299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-16795075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-17016212,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-18349632,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-19328796,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-2347923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-3472348,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-6122163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-6375546,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-7629985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-8173367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-8402094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105579-9771669
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1531-5037
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
52-8
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:20105579-Anal Canal,
pubmed-meshheading:20105579-Animals,
pubmed-meshheading:20105579-Biomedical Engineering,
pubmed-meshheading:20105579-Cells, Cultured,
pubmed-meshheading:20105579-Disease Models, Animal,
pubmed-meshheading:20105579-Fecal Incontinence,
pubmed-meshheading:20105579-Female,
pubmed-meshheading:20105579-Fibroblast Growth Factor 2,
pubmed-meshheading:20105579-Humans,
pubmed-meshheading:20105579-Manometry,
pubmed-meshheading:20105579-Mice,
pubmed-meshheading:20105579-Mice, Inbred C57BL,
pubmed-meshheading:20105579-Muscle, Smooth,
pubmed-meshheading:20105579-Myocytes, Smooth Muscle,
pubmed-meshheading:20105579-Prosthesis Design,
pubmed-meshheading:20105579-Prosthesis Implantation,
pubmed-meshheading:20105579-Tissue Culture Techniques,
pubmed-meshheading:20105579-Tissue Engineering
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pubmed:year |
2010
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pubmed:articleTitle |
Surgical implantation of a bioengineered internal anal sphincter.
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pubmed:affiliation |
Section of Pediatric Surgery, University of Michigan, Mott Children's Hospital F3970, Box 0245, Ann Arbor, MI 48109-0245, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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