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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-2-18
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pubmed:abstractText |
The contribution of low frequency drug-resistant human immunodeficiency virus type 1 (HIV-1) variants to failure of antiretroviral therapy is not well defined in treatment-experienced patients. We sought to detect minor nonnucleoside reverse-transcriptase inhibitor (NNRTI)-resistant variants at the initiation of multidrug efavirenz-containing therapy in both NNRTI-naive and NNRTI-experienced patients and to determine their association with virologic response.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-10681363,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-11333879,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-11413308,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-11751241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-12095381,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-12167680,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-12824352,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-1372083,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-14562852,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-14694092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-15635002,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-16514300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-16652319,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-16825395,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-16946457,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-17215531,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-18301062,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-18549313,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-18666824,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-19133800,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-19133804,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-19210162,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-20102273,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-7541846,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-7816094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-7824947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-7984417,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-8892912,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-9207020,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-9521921,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20102272-9521922
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1537-6613
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pubmed:author |
pubmed-author:BoltzValerie FVF,
pubmed-author:CoffinJohn MJM,
pubmed-author:HalvasElias KEK,
pubmed-author:HammerScott MSM,
pubmed-author:KearneyMaryM,
pubmed-author:MellorsJohn WJW,
pubmed-author:NissleyDwightD,
pubmed-author:PalmerSarahS,
pubmed-author:VaidaFlorinF,
pubmed-author:WantmanMichaelM,
pubmed-author:WiegandAnnA
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pubmed:issnType |
Electronic
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pubmed:volume |
201
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
672-80
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pubmed:dateRevised |
2011-7-25
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pubmed:meshHeading |
pubmed-meshheading:20102272-Anti-HIV Agents,
pubmed-meshheading:20102272-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:20102272-Benzoxazines,
pubmed-meshheading:20102272-Drug Resistance, Viral,
pubmed-meshheading:20102272-Genetic Variation,
pubmed-meshheading:20102272-HIV Infections,
pubmed-meshheading:20102272-HIV Reverse Transcriptase,
pubmed-meshheading:20102272-HIV-1,
pubmed-meshheading:20102272-Humans,
pubmed-meshheading:20102272-Mutation, Missense,
pubmed-meshheading:20102272-Plasma,
pubmed-meshheading:20102272-Polymerase Chain Reaction,
pubmed-meshheading:20102272-Selection, Genetic,
pubmed-meshheading:20102272-Sequence Analysis, DNA,
pubmed-meshheading:20102272-Treatment Failure
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pubmed:year |
2010
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pubmed:articleTitle |
Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment- experienced patients.
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pubmed:affiliation |
Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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