rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2010-4-12
|
pubmed:abstractText |
LPIN1 is the phosphatidic acid phosphatase that produces 1,2-diacylglycerol, and thus it is related to the synthesis of triglycerides in the adipocyte. LPIN1 has a role in lipid synthesis and nuclear receptor coactivation, both of which may be involved in lipid homeostasis and metabolism. Among others, hypoxia and endoplasmic reticulum (ER) stress are being shown to be related to the adipose dysfunction found in human obesity.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1476-5497
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
34
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
679-86
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:20101248-Adipocytes,
pubmed-meshheading:20101248-Blotting, Western,
pubmed-meshheading:20101248-Body Mass Index,
pubmed-meshheading:20101248-Cell Hypoxia,
pubmed-meshheading:20101248-Endoplasmic Reticulum,
pubmed-meshheading:20101248-Female,
pubmed-meshheading:20101248-Gene Expression,
pubmed-meshheading:20101248-Humans,
pubmed-meshheading:20101248-Insulin Resistance,
pubmed-meshheading:20101248-Intra-Abdominal Fat,
pubmed-meshheading:20101248-Lipid Metabolism,
pubmed-meshheading:20101248-Male,
pubmed-meshheading:20101248-Middle Aged,
pubmed-meshheading:20101248-Nuclear Proteins,
pubmed-meshheading:20101248-Obesity,
pubmed-meshheading:20101248-PPAR alpha,
pubmed-meshheading:20101248-Phosphatidate Phosphatase,
pubmed-meshheading:20101248-Subcutaneous Fat
|
pubmed:year |
2010
|
pubmed:articleTitle |
Relation between human LPIN1, hypoxia and endoplasmic reticulum stress genes in subcutaneous and visceral adipose tissue.
|
pubmed:affiliation |
Unitat de Recerca, Hospital Universitari de Tarragona Joan XXIII, IISPV, Tarragona, Spain. mmiranda.hj23.ics@gencat.cat
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|