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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-5-9
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pubmed:abstractText |
The intrinsic innervation of the human uterine artery was investigated histochemically, and the motor responses to some of the demonstrated peptides and other humoral factors were studied on isolated vascular preparations. There were nerves with specific immunoreactivities for tyrosine hydroxylase, dopamine beta-hydroxylase, neuropeptide-Y (NPY), vasoactive intestinal peptide (VIP) and peptide histidine methionine, and enzymatic reactivity for acetylcholine esterase. The most effective stimulator of smooth muscle contractility was arginine vasopressin followed in order by oxytocin, noradrenaline together with NPY, noradrenaline alone and dopamine. No effect was seen with acetylcholine and tyrosine, and VIP caused inconsistent relaxation of contractile activity induced by PGF2 alpha. These results suggest that the uterine blood flow is regulated by complex interactions of factors, some occurring in nerve terminals and some being circulating humoral factors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0378-7346
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
30-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2010112-Adult,
pubmed-meshheading:2010112-Arteries,
pubmed-meshheading:2010112-Dose-Response Relationship, Drug,
pubmed-meshheading:2010112-Female,
pubmed-meshheading:2010112-Fluorescent Antibody Technique,
pubmed-meshheading:2010112-Humans,
pubmed-meshheading:2010112-Middle Aged,
pubmed-meshheading:2010112-Muscle, Smooth, Vascular,
pubmed-meshheading:2010112-Muscle Contraction,
pubmed-meshheading:2010112-Neuropeptides,
pubmed-meshheading:2010112-Regional Blood Flow,
pubmed-meshheading:2010112-Uterus,
pubmed-meshheading:2010112-Vasoconstrictor Agents
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pubmed:year |
1991
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pubmed:articleTitle |
Innervation of the human uterine artery and contractile responses to neuropeptides.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, University Hospital of Lund, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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