Linked Life Data

2010039

Source:http://linkedlifedata.com/resource/pubmed/id/2010039

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1991-5-3
pubmed:abstractText
Hybrid embryos were derived from reciprocal crosses of Strongylocentrotus purpuratus and Lytechinus pictus sea urchins. The expression of proteins specific for L. pictus was restricted in these hybrid embryos, while this was not so for most proteins specific for S. purpuratus. In particular, the aboral ectoderm-specific calcium-binding protein Spec1 was expressed at normal levels in hybrid embryos, but its L. pictus homologue, LpS1, was considerably reduced. LpS1 mRNA accumulated in hybrid plutei to only 4-5% of its normal level. Transcription of the LpS1 gene was substantially reduced in hybrid embryos, as determined by a nuclear RNA run-on assay. Southern blot analysis of genomic DNA indicated that there was no detectable loss or rearrangement of LpS1 DNA in hybrid embryos. Thus, the Spec1 gene is expressed normally in hybrid embryos, but the transcription of its homologue, the LpS1 gene, is considerably restricted.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0012-1606
pubmed:author
pubmed:issnType
Print
pubmed:volume
144
pubmed:geneSymbol
Spec1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
405-11
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Restricted expression of the Lytechinus pictus Spec1 gene homologue in reciprocal hybrid embryos with Strongylocentrotus purpuratus.
pubmed:affiliation
Department of Biology, McGill University, Montreal, Canada.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't