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rdf:type |
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lifeskim:mentions |
umls-concept:C0004057,
umls-concept:C0008976,
umls-concept:C0030705,
umls-concept:C0034656,
umls-concept:C0247025,
umls-concept:C0348016,
umls-concept:C0392756,
umls-concept:C0443252,
umls-concept:C0521654,
umls-concept:C0948008,
umls-concept:C1280500
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pubmed:issue |
3
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pubmed:dateCreated |
2010-2-12
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|
pubmed:abstractText |
Thrombolysis with rt-PA is the only approved pharmacological therapy for acute ischemic stroke presently administrable in a 3-hour window (very recently extended to 4.5 h). After this time, the choice is limited to endovascular treatment and antiplatelet drugs, mainly aspirin (ASA), the efficacy of which in the acute phase of stroke has poorly been evaluated. We compared the efficacy of tirofiban, a GP-IIb/IIIa inhibitor, and ASA, with both drugs being administered within 6 h.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Feb
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pubmed:issn |
1421-9786
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pubmed:author |
pubmed-author:BoitiCC,
pubmed-author:BoruttiGG,
pubmed-author:CazzanigaMM,
pubmed-author:FalaschiFF,
pubmed-author:MaestroniAA,
pubmed-author:MandelliCC,
pubmed-author:ManganaroDD,
pubmed-author:MonzaniVV,
pubmed-author:RossiPP,
pubmed-author:TorganoGG,
pubmed-author:ZeccaBB,
pubmed-author:ZilioliEE
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pubmed:copyrightInfo |
Copyright 2010 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
275-81
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pubmed:meshHeading |
pubmed-meshheading:20090319-Aged,
pubmed-meshheading:20090319-Aged, 80 and over,
pubmed-meshheading:20090319-Aspirin,
pubmed-meshheading:20090319-Brain Ischemia,
pubmed-meshheading:20090319-Chi-Square Distribution,
pubmed-meshheading:20090319-Disability Evaluation,
pubmed-meshheading:20090319-Double-Blind Method,
pubmed-meshheading:20090319-Drug Administration Schedule,
pubmed-meshheading:20090319-Drug Therapy, Combination,
pubmed-meshheading:20090319-Early Termination of Clinical Trials,
pubmed-meshheading:20090319-Female,
pubmed-meshheading:20090319-Fibrinolytic Agents,
pubmed-meshheading:20090319-Hospital Mortality,
pubmed-meshheading:20090319-Humans,
pubmed-meshheading:20090319-Intracranial Hemorrhages,
pubmed-meshheading:20090319-Italy,
pubmed-meshheading:20090319-Male,
pubmed-meshheading:20090319-Middle Aged,
pubmed-meshheading:20090319-Platelet Aggregation Inhibitors,
pubmed-meshheading:20090319-Platelet Glycoprotein GPIIb-IIIa Complex,
pubmed-meshheading:20090319-Recovery of Function,
pubmed-meshheading:20090319-Stroke,
pubmed-meshheading:20090319-Time Factors,
pubmed-meshheading:20090319-Treatment Outcome,
pubmed-meshheading:20090319-Tyrosine
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pubmed:year |
2010
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pubmed:articleTitle |
Effect of intravenous tirofiban and aspirin in reducing short-term and long-term neurologic deficit in patients with ischemic stroke: a double-blind randomized trial.
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pubmed:affiliation |
Department of Emergency Medicine, Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli e Regina Elena, Milano, Italy. giuseppe.torgano@policlinico.mi.it
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Multicenter Study
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