Linked Life Data

20089425

Source:http://linkedlifedata.com/resource/pubmed/id/20089425

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-2-28
pubmed:abstractText
Pulmonary dysfunction was evaluated in pigs infected with porcine reproductive and respiratory syndrome virus (PRRSV, isolate VR-2332) and compared to clinical and pathological findings. Infected pigs developed fever, reduced appetite, respiratory distress and dullness at 9 days post-inoculation (dpi). Non-invasive pulmonary function tests using impulse oscillometry and rebreathing of test gases (He, CO) revealed peripheral airway obstruction, reduced lung compliance and reduced lung CO-transfer factor. PRRSV-induced pulmonary dysfunction was most marked at 9-18 dpi and was accompanied by a significantly increased respiratory rate and decreased tidal volume. Expiration was affected more than inspiration. On histopathological examination, multifocal areas of interstitial pneumonia (more severe and extensive at 10 dpi than 21 dpi) were identified as a possible structural basis for reduced lung compliance and gas exchange disturbances.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1532-2971
pubmed:author
pubmed:copyrightInfo
Copyright © 2009 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
187
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
310-9
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Respiratory function and pulmonary lesions in pigs infected with porcine reproductive and respiratory syndrome virus.
pubmed:affiliation
Institute of Molecular Pathogenesis in the Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Naumburger Str 96a, 07743 Jena, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't