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pubmed-article:20084527pubmed:abstractTextNonalcoholic steatohepatitis (NASH) is a feature of metabolic syndrome. Advanced glycation end-products (AGEs) are formed by the Maillard reaction, which contributes to aging and to certain pathological complications of diabetes. A recent study has suggested that glyceraldehyde-derived AGEs (Glycer-AGEs) are elevated in the sera of patients with NASH. Furthermore, immunohistochemistry of Glycer-AGEs showed intense staining in the livers of patients with NASH. The present study aimed to examine the effect of intracellular Glycer-AGEs on hepatocellular carcinoma (Hep3B) cells.lld:pubmed
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pubmed-article:20084527pubmed:articleTitleThe formation of intracellular glyceraldehyde-derived advanced glycation end-products and cytotoxicity.lld:pubmed
pubmed-article:20084527pubmed:affiliationDepartment of Pathophysiological Science, Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, 920-1181, Japan.lld:pubmed
pubmed-article:20084527pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20084527pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed