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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-2-15
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pubmed:abstractText |
Gastro-Esophageal Reflux Disease (GERD) defined as a condition that develops when the reflux of stomach contents causes troublesome symptoms and/or complications. Many drugs are used for the treatment of GERD such as omeprazole (a proton pump inhibitor) which is a widely used antiulcer drug demonstrated to protect against esophageal mucosal injury. Melatonin has been found to protect the gastrointestinal mucosa from oxidative damage caused by reactive oxygen species in different experimental ulcer models. The aim of this study is to evaluate the role of exogenous melatonin in the treatment of reflux disease in humans either alone or in combination with omeprazole therapy.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20082715-11270483,
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-230X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7
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pubmed:dateRevised |
2010-9-28
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pubmed:meshHeading |
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pubmed:year |
2010
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pubmed:articleTitle |
The potential therapeutic effect of melatonin in Gastro-Esophageal Reflux Disease.
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pubmed:affiliation |
Gastro-Enterology Surgical Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt. tharwat@mans.edu.eg
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pubmed:publicationType |
Journal Article,
Controlled Clinical Trial
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