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pubmed-article:20079890pubmed:abstractTextCortical glutamate levels are elevated in bipolar disorder, but the interpretation of this increase is unclear because glutamate has metabolic as well as neurotransmitter roles. We investigated this by measuring vesicular glutamate transporter 1 (VGluT1) expression, which reflects activity at glutamate synapses. We also measured netrin-G1 and netrin-G2 messenger RNAs because these genes are involved in the formation and plasticity of glutamatergic connections.lld:pubmed
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pubmed-article:20079890pubmed:copyrightInfoCopyright 2010 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.lld:pubmed
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pubmed-article:20079890pubmed:articleTitleMarkers of glutamate synaptic transmission and plasticity are increased in the anterior cingulate cortex in bipolar disorder.lld:pubmed
pubmed-article:20079890pubmed:affiliationDepartment of Psychiatry, University of Oxford, Oxford, United Kingdom.lld:pubmed
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