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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-4-30
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pubmed:abstractText |
We studied prospectively the ascitic fluid of 47 patients. Thirty-five were cirrhotics (group A) and 12 had malignant peritonitis (group B). All ascitic fluid samples were initially uninfected. We measured opsonic activity by a chemiluminescent assay, and chemoattractant activity by the under agarose technique. We also measured ascitic concentrations of C3, C4, fibronectin, C-reactive protein, immunoglobulins G, A and M and total proteins. All patients were followed throughout the presence of ascites. None of the group B patients developed peritoneal infection, nor did 23 of the group A patients (group A2). Twelve group A patients (group A1) developed spontaneous bacterial peritonitis (SBP), four of them with recurrence. All indices except immunoglobulins A and M were significantly different between group A and group B patients. Comparing group A1 and group A2, only chemoattractant activity and concentrations of total proteins and C3 were significantly lower in group A1. Using a multivariate analysis with Cox's model, only C3 concentration had an independent predictive value for occurrence of SBP in cirrhotic patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0168-8278
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
45-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2007775-Aged,
pubmed-meshheading:2007775-Ascitic Fluid,
pubmed-meshheading:2007775-Chemotactic Factors,
pubmed-meshheading:2007775-Chemotaxis,
pubmed-meshheading:2007775-Complement C3,
pubmed-meshheading:2007775-Female,
pubmed-meshheading:2007775-Humans,
pubmed-meshheading:2007775-Liver Cirrhosis,
pubmed-meshheading:2007775-Male,
pubmed-meshheading:2007775-Middle Aged,
pubmed-meshheading:2007775-Multivariate Analysis,
pubmed-meshheading:2007775-Opsonin Proteins,
pubmed-meshheading:2007775-Peritonitis,
pubmed-meshheading:2007775-Prospective Studies
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pubmed:year |
1991
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pubmed:articleTitle |
Chemoattractant and opsonic activity in ascitic fluid. A study in 47 patients with cirrhosis or malignant peritonitis.
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pubmed:affiliation |
Service d'Hépato-Gastroentérologie, Hôpital Jean Verdier, Bondy, France.
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pubmed:publicationType |
Journal Article,
Comparative Study
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