Linked Life Data

20074465

Source:http://linkedlifedata.com/resource/pubmed/id/20074465

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-1-15
pubmed:abstractText
Microbial penetration inside the implants internal cavity produces a bacterial reservoir that is associated with an area of inflamed connective tissue facing the fixture-abutment junction. The aim of this clinical trial is to evaluate the effectiveness of a 1 percent chlorhexidine gel on the internal bacterial contamination of implants with screw-retained abutments and on the level of AST secreted in peri-implant crevicular fluid. Twenty-five patients (aged 29 to 58 years) each received one implant. Three months after the end of the restorative treatment, and immediately after a clinical and radiographic examination and the abutment removal, microbiological samples were obtained from the internal part of each fixture and biochemical samples were collected by peri-implant sulci. The patients were then divided into two groups: the control (CG; n=10) and test (TG; n=15) groups. The CG had the abutment screwed into place and the crown cemented without any further intervention. In contrast, before the abutment placement and screw tightening, the TG had the internal part of the fixture filled with a 1 percent chlorhexidine gel. Three months later, the same clinical, microbiological and biochemical procedures were repeated in both groups. Total bacterial count, specific pathogens and AST activity were detected. The clinical parameters remained stable throughout the study. From baseline to the 3-month examination, the total bacterial counts underwent a significant reduction only in the TG. In contrast, the AST activity showed a significant increase in the CG. The administration of a 1% chlorhexidine gel appears to be an effective method for the reduction of bacterial colonization of the implant cavity and for safeguarding the health status of peri-implant tissue over a 3-month administration period.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0394-6320
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1019-26
pubmed:meshHeading
pubmed-meshheading:20074465-Adult, pubmed-meshheading:20074465-Anti-Infective Agents, Local, pubmed-meshheading:20074465-Aspartate Aminotransferases, pubmed-meshheading:20074465-Biological Markers, pubmed-meshheading:20074465-Chlorhexidine, pubmed-meshheading:20074465-Colony Count, Microbial, pubmed-meshheading:20074465-Crowns, pubmed-meshheading:20074465-Dental Abutments, pubmed-meshheading:20074465-Dental Implants, pubmed-meshheading:20074465-Female, pubmed-meshheading:20074465-Gels, pubmed-meshheading:20074465-Humans, pubmed-meshheading:20074465-Longitudinal Studies, pubmed-meshheading:20074465-Male, pubmed-meshheading:20074465-Middle Aged, pubmed-meshheading:20074465-Prosthesis-Related Infections, pubmed-meshheading:20074465-Ribotyping, pubmed-meshheading:20074465-Time Factors, pubmed-meshheading:20074465-Treatment Outcome
pubmed:articleTitle
Microbiological and biochemical effectiveness of an antiseptic gel on the bacterial contamination of the inner space of dental implants: a 3-month human longitudinal study.
pubmed:affiliation
Oral Microbiology Laboratory, Department of Biomedical Sciences, G. d'Annunzio, University of Chieti-Pescara, Chieti, Italy. simonetta.dercole@virgilio.it
pubmed:publicationType
Journal Article, Controlled Clinical Trial