Source:http://linkedlifedata.com/resource/pubmed/id/20074440
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5 Suppl 56
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pubmed:dateCreated |
2010-1-15
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pubmed:abstractText |
Fibromyalgia syndrome (FM) is an idiopathic chronic pain syndrome characterised by widespread nonarticular musculoskeletal pain, generalised tender points, in the absence of inflammatory or structural musculoskeletal abnormalities, accompanied by a constellation of symptoms that include fatigue and disturbances of sleep and mood. Catechol-O-methyltransferase (COMT) is the major catecholamine-clearing pathway and involved in the mediation of pain perception in humans, and the hypothesized role of pain perception in FM. The association between Val/Met polymorphism at the COMT gene was evaluated in FM disorder.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S51-6
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pubmed:meshHeading |
pubmed-meshheading:20074440-Adult,
pubmed-meshheading:20074440-Aged,
pubmed-meshheading:20074440-Alleles,
pubmed-meshheading:20074440-Analysis of Variance,
pubmed-meshheading:20074440-Catechol O-Methyltransferase,
pubmed-meshheading:20074440-Chi-Square Distribution,
pubmed-meshheading:20074440-Female,
pubmed-meshheading:20074440-Fibromyalgia,
pubmed-meshheading:20074440-Genetic Predisposition to Disease,
pubmed-meshheading:20074440-Genome-Wide Association Study,
pubmed-meshheading:20074440-Genotype,
pubmed-meshheading:20074440-Humans,
pubmed-meshheading:20074440-Middle Aged,
pubmed-meshheading:20074440-Phenotype,
pubmed-meshheading:20074440-Polymorphism, Single Nucleotide
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pubmed:articleTitle |
The relationship between a common catechol-O-methyltransferase (COMT) polymorphism val(158) met and fibromyalgia.
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pubmed:affiliation |
Ministry of Health Mental Health Center, Anxiety and Stress Research Unit, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel. hagitc@bgu.ac.il
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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