Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-5-1
pubmed:abstractText
Multifetal pregnancy reductions were performed during the first trimester of pregnancy in 26 patients. Transabdominal intrathoracic KC1 injections were performed in 23 cases, and transcervical aspirations in 3 cases. There were 4 miscarriages (15%) during the second trimester, 18 pregnancies ended in 33 births, 4 pregnancies are going on uneventfully and are beyond 32 weeks. There was no maternal morbidity related to the procedure; fetal morbidity has been mild.
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/Abortion, Induced, http://linkedlifedata.com/resource/pubmed/keyword/Clinical Research, http://linkedlifedata.com/resource/pubmed/keyword/Demographic Factors, http://linkedlifedata.com/resource/pubmed/keyword/ETHICS, http://linkedlifedata.com/resource/pubmed/keyword/Family Planning, http://linkedlifedata.com/resource/pubmed/keyword/Fertility, http://linkedlifedata.com/resource/pubmed/keyword/Fertility Control, Postconception, http://linkedlifedata.com/resource/pubmed/keyword/Fertility Measurements, http://linkedlifedata.com/resource/pubmed/keyword/Fetal Death, http://linkedlifedata.com/resource/pubmed/keyword/In Vitro, http://linkedlifedata.com/resource/pubmed/keyword/Mortality, http://linkedlifedata.com/resource/pubmed/keyword/Multiple Birth--complications, http://linkedlifedata.com/resource/pubmed/keyword/Ovum Transport, http://linkedlifedata.com/resource/pubmed/keyword/Population, http://linkedlifedata.com/resource/pubmed/keyword/Population Dynamics, http://linkedlifedata.com/resource/pubmed/keyword/Reproduction, http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology, http://linkedlifedata.com/resource/pubmed/keyword/Unwanted Births
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0301-2115
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
183-7
pubmed:dateRevised
2006-11-15
pubmed:otherAbstract
PIP: In spite of the successful results of fetal reduction, the author's express concern that the practice not become a part of reproduction management, but as a practice to help infertile couples and prevent the unwanted effects of multiple pregnancies. Since 1977 there has been the ability to promote fertility through use of drugs such as clomiphene citrate and personal and in vitro fertilization with the consequence in multiple embryos. The risks to the mother may be pre-eclampsia, post partum hemorrhage, and thrombophlebitis, and/or fetal pre-maturity, immaturity, and perinatal morbidity and mortality. SInce 1986 fetal reduction techniques have been available. This imposes ethical difficulties. The authors report the results of 22 Belgian patients, who carried 87 fetuses between 1985 and 1989, and received multiple pregnancy reduction (MPR). Of these, 4 are still pregnant at 32 weeks, 4 were lost completely and 1 lost in utero, and 33 live births. The live birth rate was 82% with mild morbidity. 78% were low birth weights including 2 under 1000 grams, but with no losses. It appears from the available evidence that the 15% lost is comparable. The procedure, which is described, was changes from transcervical aspiration to intra thoracic KC1 (potassium chloride) injection due to concern for vaginal bacterial growth, and the safe affects on the remaining fetuses. Complication during pregnancy included three patients with pre- eclampsia, but delivered successfully, and 1 with a Shirodkar cerclage at 20 weeks and with ruptured membranes at 37 weeks, but delivered successfully, and 1 preterm labor at 22 weeks who delivered successfully after 28 weeks with 1 dying in utero. She has been infused with beta- mimetics and maintained on indomethacin in the Trendelenburg position.
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Multifetal pregnancy reduction: a Belgian experience.
pubmed:affiliation
Department of Obstetrics and Gynecology, Hôpital Erasme, Free University of Brussels, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't