Linked Life Data

20074315

Source:http://linkedlifedata.com/resource/pubmed/id/20074315

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:20074315rdf:typepubmed:Citationlld:pubmed
pubmed-article:20074315lifeskim:mentionsumls-concept:C0043189lld:lifeskim
pubmed-article:20074315lifeskim:mentionsumls-concept:C0205419lld:lifeskim
pubmed-article:20074315lifeskim:mentionsumls-concept:C0332281lld:lifeskim
pubmed-article:20074315lifeskim:mentionsumls-concept:C0013138lld:lifeskim
pubmed-article:20074315lifeskim:mentionsumls-concept:C0086860lld:lifeskim
pubmed-article:20074315lifeskim:mentionsumls-concept:C0456389lld:lifeskim
pubmed-article:20074315lifeskim:mentionsumls-concept:C1882417lld:lifeskim
pubmed-article:20074315pubmed:issue4lld:pubmed
pubmed-article:20074315pubmed:dateCreated2010-5-11lld:pubmed
pubmed-article:20074315pubmed:abstractTextBody size often shows adaptive clines in many ectotherms across altitude and latitude, but little is known about the genetic basis of these adaptive clines. Here we identify a polymorphism in the Dca (Drosophila cold acclimation) gene in Drosophila melanogaster that influences wing size, affects wing:thorax allometry and also controls a substantial proportion of the clinal wing-size variation. A polymorphism in the promoter region of Dca had two common alleles showing strong reciprocal clinal variation in frequency with latitude along the east coast of Australia. The Dca-237 allele increased towards the tropics where wing size is smaller. A within-population association study highlighted that an increase in the frequency of this allele decreased wing size but did not influence thorax size. A manipulated increase in the level of expression of Dca achieved through UAS-GAL4 was associated with a decrease in wing size but had no effect on thorax size. This was consistent with higher Dca expression levels in family lines with higher frequency of the Dca-237 allele. Genetic variation in the promoter region of the Dca gene appears to influence adaptive size variation in the eastern Australian cline of Drosophila melanogaster and accounts for more than 10% of the genetic variation in size within and between populations.lld:pubmed
pubmed-article:20074315pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20074315pubmed:languageenglld:pubmed
pubmed-article:20074315pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20074315pubmed:citationSubsetIMlld:pubmed
pubmed-article:20074315pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20074315pubmed:statusMEDLINElld:pubmed
pubmed-article:20074315pubmed:monthFeblld:pubmed
pubmed-article:20074315pubmed:issn1365-294Xlld:pubmed
pubmed-article:20074315pubmed:authorpubmed-author:HoffmannA AAAlld:pubmed
pubmed-article:20074315pubmed:authorpubmed-author:McKechnieS...lld:pubmed
pubmed-article:20074315pubmed:authorpubmed-author:HSUF YFYlld:pubmed
pubmed-article:20074315pubmed:authorpubmed-author:JensenL TLTlld:pubmed
pubmed-article:20074315pubmed:authorpubmed-author:CarroliGGlld:pubmed
pubmed-article:20074315pubmed:authorpubmed-author:JohnsonT KTKlld:pubmed
pubmed-article:20074315pubmed:authorpubmed-author:XieB WBWlld:pubmed
pubmed-article:20074315pubmed:authorpubmed-author:BlacketM JMJlld:pubmed
pubmed-article:20074315pubmed:authorpubmed-author:RakoLLlld:pubmed
pubmed-article:20074315pubmed:authorpubmed-author:SongS VSVlld:pubmed
pubmed-article:20074315pubmed:issnTypeElectroniclld:pubmed
pubmed-article:20074315pubmed:volume19lld:pubmed
pubmed-article:20074315pubmed:ownerNLMlld:pubmed
pubmed-article:20074315pubmed:authorsCompleteYlld:pubmed
pubmed-article:20074315pubmed:pagination775-84lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:meshHeadingpubmed-meshheading:20074315...lld:pubmed
pubmed-article:20074315pubmed:year2010lld:pubmed
pubmed-article:20074315pubmed:articleTitleA clinally varying promoter polymorphism associated with adaptive variation in wing size in Drosophila.lld:pubmed
pubmed-article:20074315pubmed:affiliationCentre for Environmental Stress and Adaptation Research, School of Biological Sciences, Monash University, Vic. 3800 Australia. stephen.mckechnie@sci.monash.edu.aulld:pubmed
pubmed-article:20074315pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20074315pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:20074315lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:20074315lld:pubmed