Source:http://linkedlifedata.com/resource/pubmed/id/20073019
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2010-1-14
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pubmed:abstractText |
The clinical course of multiple sclerosis (MS) varies widely. The natural history of the disease has shown that approximately 50% of patients that begin with a relapsing-remitting clinical course will have a progressive course about 10 years after disease onset and will need some kind of aid to walk. The expression of apolipoprotein E (ApoE) increases in nerve tissue undergoing regeneration and the ApoE epsilon-4 allele is associated with abnormal neural repair. Several different reports indicate that the ApoE epsilon-4 allele is associated with a greater progression of disability in patients with MS, although this is still a matter of debate.
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pubmed:language |
spa
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1576-6578
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
19-22
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pubmed:meshHeading |
pubmed-meshheading:20073019-Adolescent,
pubmed-meshheading:20073019-Adult,
pubmed-meshheading:20073019-Alleles,
pubmed-meshheading:20073019-Apolipoprotein E4,
pubmed-meshheading:20073019-Apolipoproteins E,
pubmed-meshheading:20073019-Disease Progression,
pubmed-meshheading:20073019-Female,
pubmed-meshheading:20073019-Genotype,
pubmed-meshheading:20073019-Humans,
pubmed-meshheading:20073019-Male,
pubmed-meshheading:20073019-Mexico,
pubmed-meshheading:20073019-Middle Aged,
pubmed-meshheading:20073019-Multiple Sclerosis,
pubmed-meshheading:20073019-Nerve Regeneration,
pubmed-meshheading:20073019-Severity of Illness Index,
pubmed-meshheading:20073019-Young Adult
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pubmed:articleTitle |
[The absence of a relation between apolipoprotein E genotypes and the severity of multiple sclerosis in Mexican patients].
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pubmed:affiliation |
Laboratorio Clínico de Enfermedades Neurodegenerativas, Instituto Nacional de Neurología y Neurocirugía. México DF, México. coronav@servidor.unam.mx
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pubmed:publicationType |
Journal Article,
English Abstract
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