Linked Life Data

20071111

Source:http://linkedlifedata.com/resource/pubmed/id/20071111

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-3
pubmed:dateCreated
2010-3-29
pubmed:abstractText
The present study introduced a procedure of small volume liquid extraction of amphetamines, including amphetamine (AM); methamphetamine (MA); 3,4-methylenedioxyamphetamine (MDA); 3,4-methylenemethamphtamine (MDMA), in saliva. Extraction efficiencies were compared between the conventional volume liquid phase extraction (LPE) and the small volume one, in which <100 microL solvent was used instead of several milliliters in LPE. Conditions such as types and volumes of organic solvent used in the extraction and concentrations of target analytes in aqueous samples were examined. Results showed that small volume liquid extraction had an enrichment effect on the analytes. After extraction, the organic phase was either directly drawn out for GC analysis, or partially transferred to another vial for derivatization. Detection limits were less than 5 ng/mL in saliva using GC/MS-SIM after derivatization. RSD (of peak area ratios) was less than 15% at all drug concentrations. The method was used in the analyses of saliva collected from amphetamine abusers, and was proven to be practical for detecting trace amounts of amphetamines in saliva.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1872-6283
pubmed:author
pubmed:copyrightInfo
Copyright 2009 Elsevier Ireland Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
197
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
80-4
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Small volume liquid extraction of amphetamines in saliva.
pubmed:affiliation
Forensic Science Department, Chinese Peoples Public Security University, Beijing, PR China. mengpinjia@163.com
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't