Linked Life Data

2006984

Source:http://linkedlifedata.com/resource/pubmed/id/2006984

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-5-1
pubmed:abstractText
The effect of body temperature on ethanol (ETOH) or ethanol plus pentobarbital (ETOH/PB) lethality was investigated in C57BL/6J mice. Decreasing ambient temperatures from 35-20 degrees C, decreased rectal temperatures from 38-20 degrees C and increased 8-hour survival from 0-93% for ETOH-treated and from 0-100% for ETOH/PB-treated mice. ETOH and ETOH/PB animals with no hypothermia (body temperatures = 38 degrees C) had the highest lethality. Those with body temperatures between 30-32 degrees C had the highest 24-hour survival. These results suggest that controlled hypothermia may be useful in reducing lethality from ethanol or ethanol/combination overdoses.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0741-8329
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
39-41
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Body temperature influences ethanol and ethanol/pentobarbital lethality in mice.
pubmed:affiliation
Alcohol and Brain Research Laboratory, School of Pharmacy, University of Southern California, Los Angeles 90033.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.