Linked Life Data

20069538

Source:http://linkedlifedata.com/resource/pubmed/id/20069538

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-1-13
pubmed:abstractText
Methylation-sensitive single-molecule analysis of chromatin structure is a high-resolution method for studying nucleosome positioning. As described in this unit, this method allows for the analysis of the chromatin structure of unmethylated CpG islands or in vitro-remodeled nucleosomes by treatment with the CpG-specific DNA methyltransferase SssI (M.SssI), followed by bisulfite sequencing of individual progeny DNA molecules. Unlike nuclease-based approaches, this method allows each molecule to be viewed as an individual entity instead of an average population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1934-3647
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
Chapter 21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
Unit 21.17.1-16
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Methylation-sensitive single-molecule analysis of chromatin structure.
pubmed:affiliation
Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
pubmed:publicationType
Journal Article