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rdf:type |
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lifeskim:mentions |
umls-concept:C0005558,
umls-concept:C0007131,
umls-concept:C0010803,
umls-concept:C0011900,
umls-concept:C0026682,
umls-concept:C0084785,
umls-concept:C0441833,
umls-concept:C0449438,
umls-concept:C0487602,
umls-concept:C0520510,
umls-concept:C0796357,
umls-concept:C1384616,
umls-concept:C1414313,
umls-concept:C1422009,
umls-concept:C1999270,
umls-concept:C2347318
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pubmed:issue |
4
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pubmed:dateCreated |
2010-4-1
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pubmed:abstractText |
The dichotomization of non-small cell carcinoma (NSCLC) subtype into squamous (SQCC) and adenocarcinoma (ADC) has become important in recent years and is increasingly required with regard to management. The aim of this study was to determine the utility of a panel of commercially available antibodies in refining the diagnosis on small biopsies and also to determine whether cytologic material is suitable for somatic EGFR genotyping in a prospectively analyzed series of patients undergoing investigation for suspected lung cancer.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/EGFR protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Keratin-5,
http://linkedlifedata.com/resource/pubmed/chemical/Keratin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Mucins,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/TP63 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/thyroid nuclear factor 1
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1556-1380
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
436-41
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pubmed:meshHeading |
pubmed-meshheading:20068475-Adenocarcinoma,
pubmed-meshheading:20068475-Biopsy, Fine-Needle,
pubmed-meshheading:20068475-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:20068475-Carcinoma, Squamous Cell,
pubmed-meshheading:20068475-Cytodiagnosis,
pubmed-meshheading:20068475-DNA, Neoplasm,
pubmed-meshheading:20068475-DNA Mutational Analysis,
pubmed-meshheading:20068475-Diagnosis, Differential,
pubmed-meshheading:20068475-Genotype,
pubmed-meshheading:20068475-Humans,
pubmed-meshheading:20068475-Immunoenzyme Techniques,
pubmed-meshheading:20068475-Keratin-5,
pubmed-meshheading:20068475-Keratin-6,
pubmed-meshheading:20068475-Lung Neoplasms,
pubmed-meshheading:20068475-Mucins,
pubmed-meshheading:20068475-Mutation,
pubmed-meshheading:20068475-Neoplasm Staging,
pubmed-meshheading:20068475-Nuclear Proteins,
pubmed-meshheading:20068475-Polymerase Chain Reaction,
pubmed-meshheading:20068475-Prognosis,
pubmed-meshheading:20068475-Prospective Studies,
pubmed-meshheading:20068475-Receptor, Epidermal Growth Factor,
pubmed-meshheading:20068475-Retrospective Studies,
pubmed-meshheading:20068475-Sensitivity and Specificity,
pubmed-meshheading:20068475-Small Cell Lung Carcinoma,
pubmed-meshheading:20068475-Survival Rate,
pubmed-meshheading:20068475-Trans-Activators,
pubmed-meshheading:20068475-Transcription Factors,
pubmed-meshheading:20068475-Tumor Markers, Biological,
pubmed-meshheading:20068475-Tumor Suppressor Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
Refining the diagnosis and EGFR status of non-small cell lung carcinoma in biopsy and cytologic material, using a panel of mucin staining, TTF-1, cytokeratin 5/6, and P63, and EGFR mutation analysis.
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pubmed:affiliation |
Department of Histopathology, Royal Brompton Hospital, London. a.nicholson@rbht.nhs.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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