rdf:type |
|
lifeskim:mentions |
umls-concept:C0012634,
umls-concept:C0017262,
umls-concept:C0023434,
umls-concept:C0026882,
umls-concept:C0185117,
umls-concept:C0205210,
umls-concept:C0205460,
umls-concept:C1416037,
umls-concept:C1515021,
umls-concept:C2348519,
umls-concept:C2911684
|
pubmed:issue |
2
|
pubmed:dateCreated |
2010-1-15
|
pubmed:abstractText |
B-cell chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease whose outcome can be foreseen by investigating the mutational status of immunoglobulin heavy chain variable (IGHV) genes. Moreover, a different prognosis was reported for CLL expressing specific IGHV genes in the context or not of stereotyped B-cell receptors. Here we investigated novel associations between usage of specific IGHV genes and clinical features in CLL.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1078-0432
|
pubmed:author |
pubmed-author:BenedettiDaniaD,
pubmed-author:BertoniFrancescoF,
pubmed-author:BombenRiccardoR,
pubmed-author:BulianPietroP,
pubmed-author:CapelloDanielaD,
pubmed-author:CattarossiIlariaI,
pubmed-author:Dal-BoMicheleM,
pubmed-author:DeganMassimoM,
pubmed-author:Del PoetaGiovanniG,
pubmed-author:Del PrincipeMaria IlariaMI,
pubmed-author:EfremovDimitar GDG,
pubmed-author:ForconiFrancescoF,
pubmed-author:GaidanoGianlucaG,
pubmed-author:GatteiValterV,
pubmed-author:LaurentiLucaL,
pubmed-author:LucianoFabrizioF,
pubmed-author:MaffeiRossanaR,
pubmed-author:MarascaRobertoR,
pubmed-author:MarconiDanielaD,
pubmed-author:NicolosoMilena SMS,
pubmed-author:RossiDavideD,
pubmed-author:RossiFrancesca MariaFM,
pubmed-author:SozziElisaE,
pubmed-author:ZuccaEmanueleE,
pubmed-author:ZucchettoAntonellaA
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
620-8
|
pubmed:meshHeading |
pubmed-meshheading:20068100-Adult,
pubmed-meshheading:20068100-Aged,
pubmed-meshheading:20068100-Aged, 80 and over,
pubmed-meshheading:20068100-Cohort Studies,
pubmed-meshheading:20068100-Diagnosis, Differential,
pubmed-meshheading:20068100-Gene Expression Profiling,
pubmed-meshheading:20068100-Gene Expression Regulation, Leukemic,
pubmed-meshheading:20068100-Gene Rearrangement,
pubmed-meshheading:20068100-Genes, Immunoglobulin Heavy Chain,
pubmed-meshheading:20068100-Humans,
pubmed-meshheading:20068100-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:20068100-MicroRNAs,
pubmed-meshheading:20068100-Middle Aged,
pubmed-meshheading:20068100-Mutant Proteins,
pubmed-meshheading:20068100-Neoplasm Staging,
pubmed-meshheading:20068100-Prognosis
|
pubmed:year |
2010
|
pubmed:articleTitle |
Expression of mutated IGHV3-23 genes in chronic lymphocytic leukemia identifies a disease subset with peculiar clinical and biological features.
|
pubmed:affiliation |
Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico, I.R.C.C.S., Aviano (PN), Italy.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|