Linked Life Data

20066610

Source:http://linkedlifedata.com/resource/pubmed/id/20066610

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-2-10
pubmed:abstractText
Difficulties initiating and maintaining sleep as well as circadian rhythm disorders are very common in schizophrenia. Sleeping disorders occur as early signs of the first manifestation of illness as well as early signs of relapse. They bear a relation to positive symptoms and disorganisation of thought. Polysomnographic investigations with schizophrenic patients typically demonstrate a prolonged sleep-onset latency and a decrease in sleep efficiency and slow wave sleep. In particular, distortions of deep sleep can affect neocortical plasticity and cognition negatively. The considerable sleeping disorders are often not sufficiently taken into account in clinical routine. Particularly older antipsychotic medication like Haloperidol can affect the circadian and sleep-wake rhythms negatively. Therefore, pathophysiological changes of sleep within the scope of schizophrenic disorders and their potential implications are discussed in this outline. Regarding therapy, psychoeducative approaches are discussed as well as the administration of antipsychotic medication in accordance with the recommendations of sleep medicine professionals.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1439-3522
pubmed:author
pubmed:copyrightInfo
Georg Thieme Verlag KG Stuttgart * New York.
pubmed:issnType
Electronic
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
70-80
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
[Sleep disorders in schizophrenia].
pubmed:affiliation
Klinik für Psychiatrie, Psychotherapie und Psychosomatik-Memory Clinic, Vivantes Klinikum Spandau, Berlin. juergen.staedt@vivantes.de
pubmed:publicationType
Journal Article, English Abstract, Review