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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-1-12
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pubmed:abstractText |
Preventing arthritic change in a joint with an intra-articular fracture remains a challenge, especially in weight-bearing joints. Hyaluronan (HA) has been proven to be effective in relieving joint pain and improving function in chronic osteoarthritis. However, controversy still exists about its potential use in a joint with an intra-articular fracture and about whether this effect is dependent on molecular weight. We analyzed and compared the effects of two different molecular weight HAs on six osteoarthritis-related proteins expressed in fibroblast-like synoviocytes from 12 patients with tibial plateau fracture.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1529-8809
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
146-52
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pubmed:meshHeading |
pubmed-meshheading:20065770-Adolescent,
pubmed-meshheading:20065770-Adult,
pubmed-meshheading:20065770-Arthroscopy,
pubmed-meshheading:20065770-Cells, Cultured,
pubmed-meshheading:20065770-Humans,
pubmed-meshheading:20065770-Hyaluronic Acid,
pubmed-meshheading:20065770-Injections, Intra-Articular,
pubmed-meshheading:20065770-Interleukin-1beta,
pubmed-meshheading:20065770-Intra-Articular Fractures,
pubmed-meshheading:20065770-Matrix Metalloproteinase 3,
pubmed-meshheading:20065770-Menisci, Tibial,
pubmed-meshheading:20065770-Middle Aged,
pubmed-meshheading:20065770-Molecular Weight,
pubmed-meshheading:20065770-Osteoarthritis, Knee,
pubmed-meshheading:20065770-Synovial Membrane,
pubmed-meshheading:20065770-Tibial Fractures,
pubmed-meshheading:20065770-Tissue Inhibitor of Metalloproteinase-1,
pubmed-meshheading:20065770-Tissue Inhibitor of Metalloproteinase-2,
pubmed-meshheading:20065770-Tumor Necrosis Factor-alpha,
pubmed-meshheading:20065770-Viscosupplements,
pubmed-meshheading:20065770-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Effect of different molecular weight hyaluronans on osteoarthritis-related protein production in fibroblast-like synoviocytes from patients with tibia plateau fracture.
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pubmed:affiliation |
Institute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, 100 Taiwan, ROC.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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