Source:http://linkedlifedata.com/resource/pubmed/id/20061597
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2010-1-12
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pubmed:abstractText |
1D hierarchical composite mesostructures of titanate and silica were synthesized via an interfacial surfactant templating approach. Such mesostructures have complex core-shell architectures consisting of single-crystalline H(2)Ti(3)O(7) nanobelts inside the ordered mesoporous SiO(2) shell, which are nontoxic and highly biocompatible. The overall diameter of as-prepared 1D hierarchical composite mesostructures is only approx. 34.2 nm with a length over 500 nm on average. A model to explain the formation mechanism of these mesostructures has been proposed; the negatively charged surface of H(2)Ti(3)O(7) nanobelts controls the formation of the octadecyltrimethylammonium bromide (C(18)TAB) bilayer, which in turn regulates the cooperative self-assembly of silica and C(18)TAB complex micelles on the interface to produce a mesoporous silica shell. More importantly, the application of synthesized mesostructured nanocables as anticancer drug reservoirs has also been explored, which indicates that the membranes containing these mesoporous nanocables have a great potential to be used as transdermal drug delivery systems.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Bufanolides,
http://linkedlifedata.com/resource/pubmed/chemical/Delayed-Action Preparations,
http://linkedlifedata.com/resource/pubmed/chemical/Silicon Dioxide,
http://linkedlifedata.com/resource/pubmed/chemical/Surface-Active Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Titanium,
http://linkedlifedata.com/resource/pubmed/chemical/bufalin
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1361-6528
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
10
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
065604
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pubmed:meshHeading |
pubmed-meshheading:20061597-Antineoplastic Agents,
pubmed-meshheading:20061597-Bufanolides,
pubmed-meshheading:20061597-Delayed-Action Preparations,
pubmed-meshheading:20061597-Nanostructures,
pubmed-meshheading:20061597-Silicon Dioxide,
pubmed-meshheading:20061597-Surface-Active Agents,
pubmed-meshheading:20061597-Titanium
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pubmed:year |
2010
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pubmed:articleTitle |
Titanate-silica mesostructured nanocables: synthesis, structural analysis and biomedical applications.
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pubmed:affiliation |
Department of Traditional Chinese Medicine, Changhai Hospital, The Second Military Medical University, Shanghai, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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