Source:http://linkedlifedata.com/resource/pubmed/id/20054578
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2010-6-22
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pubmed:abstractText |
Ligamentous attachments maintain the normal anatomic position of the gastroesophageal (GE) junction. Failure of these elastic ligaments through an alteration in collagen synthesis, deposition, and metabolism may be a primary etiology of hiatal hernia formation. Differential expression of zinc-dependent matrix metalloproteinases (MMPs) is largely responsible for collagen remodeling. The purpose of this study was to survey baseline levels of MMPs in supporting ligaments of the GE junction from patients without hiatal hernia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1432-2218
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pubmed:author |
pubmed-author:ArifBatoolB,
pubmed-author:BruntL MichaelLM,
pubmed-author:ChisholmPhillip RPR,
pubmed-author:CurciJohn AJA,
pubmed-author:EagonChristopherC,
pubmed-author:FrisellaMargaretM,
pubmed-author:JenkinsEric DED,
pubmed-author:MatthewsBrent DBD,
pubmed-author:MelmanLoraL,
pubmed-author:MillerKathleenK,
pubmed-author:PierceRichardR
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pubmed:issnType |
Electronic
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1562-5
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
Differential regulation of MMP-2 in the gastrohepatic ligament of the gastroesophageal junction.
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pubmed:affiliation |
Department of Surgery, Section of Minimally Invasive Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box #8109, St. Louis, MO 63110, USA. melmanl@wudosis.wustl.edu
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pubmed:publicationType |
Journal Article
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