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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-4-23
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pubmed:abstractText |
The prognostic significance of the white nipple sign in variceal bleeding was evaluated prospectively in 203 separate admissions for bleeding esophageal varices in 145 cirrhotic patients. During all admissions a standardized protocol of management defined the failure of transfusion and vasoactive drugs (conservative measures) to stop bleeding and the occurrence of early rebleeding, at which time either emergency sclerotherapy or a staple transection of the esophagus was used. The finding of a white nipple in 18 admissions (9%) did not have predictive value as regards the failure of conservative measures to stop bleeding within 24 hours or rebleeding within 5 days, and there was no association with increased mortality. In one case, a white nipple was seen to occur after spontaneous cessation of a variceal venous spurt, suggesting it is a platelet-fibrin plug. The white nipple sign is diagnostic of a varix that has bled but has no adverse prognostic significance.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0016-5107
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
51-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2004684-Aged,
pubmed-meshheading:2004684-Blood Transfusion,
pubmed-meshheading:2004684-Esophageal and Gastric Varices,
pubmed-meshheading:2004684-Esophagoscopy,
pubmed-meshheading:2004684-Female,
pubmed-meshheading:2004684-Gastrointestinal Hemorrhage,
pubmed-meshheading:2004684-Humans,
pubmed-meshheading:2004684-Male,
pubmed-meshheading:2004684-Multivariate Analysis,
pubmed-meshheading:2004684-Prognosis,
pubmed-meshheading:2004684-Prospective Studies,
pubmed-meshheading:2004684-Regression Analysis,
pubmed-meshheading:2004684-Sclerotherapy,
pubmed-meshheading:2004684-Vasoconstrictor Agents
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pubmed:articleTitle |
Prognostic significance of the white nipple sign in variceal bleeding.
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pubmed:affiliation |
Hepato-biliary and Liver Transplantation Unit, Royal Free Hospital and School of Medicine, London, United Kingdom.
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pubmed:publicationType |
Journal Article,
Case Reports
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