Linked Life Data

20046708

Source:http://linkedlifedata.com/resource/pubmed/id/20046708

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-1-4
pubmed:abstractText
This paper describes the preparation of new bilayered device comprising a drug containing mucoadhesive layer and a drug free backing layer. Bilaminated films were produced by a casting/ solvent evaporation technique. The mucoadhesive layer was composed of mixture of drug and sodium alginate with or without carbopol 934 P, and backing layer was made of ethyl cellulose. The double layer structure design was expected to provide drug delivery in a unidirectional fashion to the mucosa and avoid loss of drug due to wash out with saliva. The fabricated films were subjected to in vitro drug release, in vitro permeation through porcine buccal mucosa. The bilayered films were also evaluated for mucoadhesive strength, mucoadhesive time, folding endurance, hydration studies and tensile strength.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:issn
1998-3743
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
175-9
pubmed:articleTitle
Preparation and evaluation of buccoadhesive films of atenolol.
pubmed:affiliation
Delhi Institute of Pharmaceutical Sciences and Research, Sector 3, Pushpvihar, New Delhi-110 017, India.
pubmed:publicationType
Journal Article