Source:http://linkedlifedata.com/resource/pubmed/id/20044260
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2010-2-3
|
| pubmed:abstractText |
Multidrug-resistant bacterial infections continue to be a rising global health concern. Herein is described the development of a class of novel 2-aminobenzimidazoles with antibiotic activity. These active 2-aminobenzimidazoles retain their antibiotic activity against several strains of multidrug-resistant Staphylococcus aureus and Acinetobacter baumannii when compared to susceptible strains.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
1464-3391
|
| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 2009. Published by Elsevier Ltd.
|
| pubmed:issnType |
Electronic
|
| pubmed:day |
15
|
| pubmed:volume |
18
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
663-74
|
| pubmed:meshHeading |
pubmed-meshheading:20044260-Acinetobacter baumannii,
pubmed-meshheading:20044260-Anti-Bacterial Agents,
pubmed-meshheading:20044260-Benzimidazoles,
pubmed-meshheading:20044260-Drug Resistance, Multiple, Bacterial,
pubmed-meshheading:20044260-Methicillin-Resistant Staphylococcus aureus,
pubmed-meshheading:20044260-Microbial Sensitivity Tests,
pubmed-meshheading:20044260-Molecular Conformation,
pubmed-meshheading:20044260-Small Molecule Libraries,
pubmed-meshheading:20044260-Stereoisomerism,
pubmed-meshheading:20044260-Structure-Activity Relationship
|
| pubmed:year |
2010
|
| pubmed:articleTitle |
The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii.
|
| pubmed:affiliation |
North Carolina State University Chemistry Department, 2620 Yarborough Drive, Raleigh, NC 27695-8204, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|