20042177

Source:http://linkedlifedata.com/resource/pubmed/id/20042177

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017337, umls-concept:C0205419, umls-concept:C0242383, umls-concept:C1121571, umls-concept:C1280500
pubmed:issue	3
pubmed:dateCreated	2010-2-22
pubmed:abstractText	Age-related macular degeneration (AMD) is the leading cause of blindness among older adults, in which oxidative damage may play a pivotal role. Paraoxonase 1 (PON1) protects against oxidative damage and has been evaluated for its involvement in aging diseases including AMD. This study investigated whether PON1 gene polymorphisms associate with AMD.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/EY015638, http://linkedlifedata.com/resource/pubmed/grant/EY016072, http://linkedlifedata.com/resource/pubmed/grant/R01 EY016072-04
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0370500
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Aryldialkylphosphatase, http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers, http://linkedlifedata.com/resource/pubmed/chemical/PON1 protein, human
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	1879-1891
pubmed:author	pubmed-author:Clinical Genomic And Proteomic AMD Study Group, pubmed-author:HagstromStephanie ASA, pubmed-author:PauerGayle J TGJ, pubmed-author:PeacheyNeal SNS, pubmed-author:SturgillGwen MGM
pubmed:copyrightInfo	(c) 2010 Elsevier Inc. All rights reserved.
pubmed:issnType	Electronic
pubmed:volume	149
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	513-22
pubmed:dateRevised	2011-7-20
pubmed:meshHeading	pubmed-meshheading:20042177-Aged, pubmed-meshheading:20042177-Aged, 80 and over, pubmed-meshheading:20042177-Aryldialkylphosphatase, pubmed-meshheading:20042177-Case-Control Studies, pubmed-meshheading:20042177-DNA Mutational Analysis, pubmed-meshheading:20042177-DNA Primers, pubmed-meshheading:20042177-Female, pubmed-meshheading:20042177-Genotype, pubmed-meshheading:20042177-Humans, pubmed-meshheading:20042177-Male, pubmed-meshheading:20042177-Middle Aged, pubmed-meshheading:20042177-Mutation, Missense, pubmed-meshheading:20042177-Oxidative Stress, pubmed-meshheading:20042177-Polymerase Chain Reaction, pubmed-meshheading:20042177-Polymorphism, Single Nucleotide, pubmed-meshheading:20042177-Polymorphism, Single-Stranded Conformational, pubmed-meshheading:20042177-Sequence Analysis, DNA, pubmed-meshheading:20042177-Wet Macular Degeneration
pubmed:year	2010
pubmed:articleTitle	Protective effect of paraoxonase 1 gene variant Gln192Arg in age-related macular degeneration.
pubmed:affiliation	Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural