Linked Life Data

20041785

Source:http://linkedlifedata.com/resource/pubmed/id/20041785

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2009-12-31
pubmed:abstractText
Currants and sultanas (Vitis vinifera L., Family Vitaceae) are dried vine products produced in Greece and used widely in the Mediterranean diet. We investigated the polar methanol extracts from the raisins for the antiradical activity, polyphenol content, cytotoxicity in peripheral blood mononuclear cells, total glutathione (GSH) levels, oxidized glutathione (GSSG) levels, and inhibition of low-density lipoprotein (LDL) oxidation. Extracts exhibited 1,1-diphenyl-2-picrylhydrazyl scavenging activity and inhibited tert-butylhydroperoxide (tBHP)-induced cytotoxicity, GSH decrease, and LDL oxidation. Fluorescence microscopy revealed the characteristic apoptotic patterns with tBHP and inhibition with the extracts. Elevated levels of total GSH and unaltered levels of GSSG with extract treatment demonstrated the induction of gamma-glutamylcysteine synthetase. The antioxidant activity was correlated to the polyphenolic content. Greek currants and sultanas are suggested as antioxidant components of the Mediterranean basin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1557-7600
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1302-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Antioxidant properties of raisins (Vitis vinifera L.).
pubmed:affiliation
Department of Science of Dietetics-Nutrition, Harokopio University, Athens, Greece. akaliora@hua.gr
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't