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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-12-30
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pubmed:abstractText |
Interaction of receptor for advanced glycation end products (RAGE) with advanced glycation end products (AGEs) is an important pathogenic mechanism of diabetic complications. Three mutations in the promoter region of the RAGE gene (T-429C, T-374A and a 63 bp deletion spanning from -407 to -345 nucleotides) were known to have increased transcriptional activities. We investigated the relationship between these polymorphisms and the risk of cardiovascular diseases in Chinese subjects with overt diabetic nephropathy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0301-0430
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
44-50
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20040351-Analysis of Variance,
pubmed-meshheading:20040351-Asian Continental Ancestry Group,
pubmed-meshheading:20040351-Cardiovascular Diseases,
pubmed-meshheading:20040351-Chi-Square Distribution,
pubmed-meshheading:20040351-China,
pubmed-meshheading:20040351-Diabetic Nephropathies,
pubmed-meshheading:20040351-Disease-Free Survival,
pubmed-meshheading:20040351-Genetic Predisposition to Disease,
pubmed-meshheading:20040351-Genotype,
pubmed-meshheading:20040351-Humans,
pubmed-meshheading:20040351-Kaplan-Meier Estimate,
pubmed-meshheading:20040351-Kidney Failure, Chronic,
pubmed-meshheading:20040351-Polymerase Chain Reaction,
pubmed-meshheading:20040351-Polymorphism, Genetic,
pubmed-meshheading:20040351-Proportional Hazards Models,
pubmed-meshheading:20040351-Receptors, Immunologic,
pubmed-meshheading:20040351-Risk Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Relation between polymorphisms of receptor for advanced glycation end products (RAGE) and cardiovascular diseases in Chinese patients with diabetic nephropathy.
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pubmed:affiliation |
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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