Source:http://linkedlifedata.com/resource/pubmed/id/20039897
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2010-7-20
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pubmed:abstractText |
Optimal diagnostic criteria for the 4-mg intravenous dexamethasone suppression test (IVDST) in patients with Cushing's syndrome (CS), compared with normal subjects, have not been established. We evaluated the performance of the 4-mg IVDST for differentiating CS from normal subjects and to define the responses in CS of various aetiologies. DESIGN, SUBJECTS, MEASUREMENTS: Thirty-two control subjects [normal and overweight/obese participants with or without type 2 diabetes) were prospectively studied, and data from 66 patients with Cushing's disease (CD), three with ectopic ACTH syndrome (EAS), 14 with adrenal Cushing's (AC)] and 15 with low probability of CS (LPC) from three tertiary hospitals were retrospectively evaluated. Dexamethasone was infused at 1 mg/h for 4 h. Plasma cortisol and ACTH were measured at -60 min (baseline), -5 min, +3 h, +4 h, +5 h and at +23 and +23.5 h on Day 2.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1365-2265
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
78-84
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pubmed:meshHeading |
pubmed-meshheading:20039897-ACTH Syndrome, Ectopic,
pubmed-meshheading:20039897-Adrenocorticotropic Hormone,
pubmed-meshheading:20039897-Adult,
pubmed-meshheading:20039897-Aged,
pubmed-meshheading:20039897-Cushing Syndrome,
pubmed-meshheading:20039897-Dexamethasone,
pubmed-meshheading:20039897-Female,
pubmed-meshheading:20039897-Humans,
pubmed-meshheading:20039897-Hydrocortisone,
pubmed-meshheading:20039897-Male,
pubmed-meshheading:20039897-Middle Aged
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pubmed:year |
2010
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pubmed:articleTitle |
The 4-mg intravenous dexamethasone suppression test in the diagnosis of Cushing's syndrome.
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pubmed:affiliation |
Department of Endocrinology and Diabetes, St Vincent's Hospital, Fitzroy, VIC 3065, Australia. caroline.jung@svhm.org.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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