Linked Life Data

20039862

Source:http://linkedlifedata.com/resource/pubmed/id/20039862

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-1-12
pubmed:abstractText
Allogeneic pregnancies have a survival advantage over syngeneic pregnancies, and paternal Class I MHC antigens have been implicated. In humans, HLA-C and HLA-G and E are expressed by subpopulations of fetal trophoblast. In mice, Qa-2, a Class Ib antigen, and classical H-2K antigens have been described. However, the mechanism of prevention of embryo demise in utero has not been critically assessed, and a number of conflicting ideas have not been addressed. The alphabeta T-cell receptor recognizes peptide bound to the groove in Class I MHC, and peptides have profound effects on the interaction of KIR receptors on T and NK cells with Class I MHC.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1600-0897
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
93-103
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Tolerance mechanisms in pregnancy: a reappraisal of the role of class I paternal MHC antigens.
pubmed:affiliation
Department of Medicine, McMaster University Rm 3V39, Hamilton, ON, Canada. clarkd@mcmaster.ca
pubmed:publicationType
Journal Article, Review