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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-1-13
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pubmed:abstractText |
High titers of specific anti-citrullinated protein antibodies (ACPAs) are frequently present in the serum of rheumatoid arthritis (RA) patients, but their presence in synovial fluid is less well characterized. The purpose of this study was to compare the levels of antibody to 4 well-defined citrullinated candidate RA autoantigens in serum and synovial fluid and to determine whether antibodies to one citrullinated antigen are dominant over another. Furthermore, we studied their relationships with mutated citrullinated vimentin (MCV), a newly identified RA-specific serum assay, and the classic cyclic citrullinated peptide (CCP) in the synovial fluid of well-defined HLA-DR groups.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Autoantibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Autoantigens,
http://linkedlifedata.com/resource/pubmed/chemical/Citrulline,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type II,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/ENO1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Fibrinogen,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DRB1 Chains,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides, Cyclic,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphopyruvate Hydratase,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Vimentin,
http://linkedlifedata.com/resource/pubmed/chemical/cyclic citrullinated peptide
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0004-3591
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pubmed:author |
pubmed-author:EngströmAkeA,
pubmed-author:HensenSanneS,
pubmed-author:HermanssonMonikaM,
pubmed-author:HolmdahlRikardR,
pubmed-author:KlareskogLarsL,
pubmed-author:LindbergJohanJ,
pubmed-author:LundbergKarinK,
pubmed-author:MalmströmVivianneV,
pubmed-author:SnirOmriO,
pubmed-author:ToesRené E MRE,
pubmed-author:VenablesPatrick J WPJ,
pubmed-author:WidheMonaM,
pubmed-author:von SpeeCarolineC
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pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
44-52
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20039432-Adult,
pubmed-meshheading:20039432-Aged,
pubmed-meshheading:20039432-Aged, 80 and over,
pubmed-meshheading:20039432-Arthritis, Rheumatoid,
pubmed-meshheading:20039432-Autoantibodies,
pubmed-meshheading:20039432-Autoantigens,
pubmed-meshheading:20039432-Citrulline,
pubmed-meshheading:20039432-Collagen Type II,
pubmed-meshheading:20039432-DNA-Binding Proteins,
pubmed-meshheading:20039432-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20039432-Female,
pubmed-meshheading:20039432-Fibrinogen,
pubmed-meshheading:20039432-Genotype,
pubmed-meshheading:20039432-HLA-DR Antigens,
pubmed-meshheading:20039432-HLA-DRB1 Chains,
pubmed-meshheading:20039432-Humans,
pubmed-meshheading:20039432-Male,
pubmed-meshheading:20039432-Middle Aged,
pubmed-meshheading:20039432-Mutation,
pubmed-meshheading:20039432-Peptides, Cyclic,
pubmed-meshheading:20039432-Phosphopyruvate Hydratase,
pubmed-meshheading:20039432-Synovial Fluid,
pubmed-meshheading:20039432-Tumor Markers, Biological,
pubmed-meshheading:20039432-Tumor Suppressor Proteins,
pubmed-meshheading:20039432-Vimentin,
pubmed-meshheading:20039432-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients.
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pubmed:affiliation |
Karolinska University Hospital, Karolinska Institutet at Solna, Stockholm, Sweden.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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