|
rdf:type |
|
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lifeskim:mentions |
umls-concept:C0004504,
umls-concept:C0005775,
umls-concept:C0016278,
umls-concept:C0018956,
umls-concept:C0319899,
umls-concept:C0370215,
umls-concept:C0376387,
umls-concept:C0537894,
umls-concept:C0683598,
umls-concept:C1301820,
umls-concept:C1504389,
umls-concept:C1706701
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|
pubmed:issue |
3
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|
pubmed:dateCreated |
2010-2-22
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|
pubmed:abstractText |
We describe the acquisition of flucytosine, azole, and caspofungin resistance in sequential Candida glabrata bloodstream isolates collected from a bone marrow transplant patient with clinical failure. Point mutations in C. glabrata FUR1 (CgFUR1) and CgFKS2 and overexpression of CgCDR1 and CgCDR2 were observed in resistant isolates.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
|
pubmed:issn |
1098-6596
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|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
54
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1360-2
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pubmed:dateRevised |
2010-9-2
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pubmed:meshHeading |
pubmed-meshheading:20038613-Antifungal Agents,
pubmed-meshheading:20038613-Azoles,
pubmed-meshheading:20038613-Candida glabrata,
pubmed-meshheading:20038613-Candidiasis,
pubmed-meshheading:20038613-Child,
pubmed-meshheading:20038613-Drug Resistance, Fungal,
pubmed-meshheading:20038613-Echinocandins,
pubmed-meshheading:20038613-Female,
pubmed-meshheading:20038613-Flucytosine,
pubmed-meshheading:20038613-Fungal Proteins,
pubmed-meshheading:20038613-Fungemia,
pubmed-meshheading:20038613-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:20038613-Humans,
pubmed-meshheading:20038613-Microbial Sensitivity Tests,
pubmed-meshheading:20038613-Point Mutation
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|
pubmed:year |
2010
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|
pubmed:articleTitle |
Acquisition of flucytosine, azole, and caspofungin resistance in Candida glabrata bloodstream isolates serially obtained from a hematopoietic stem cell transplant recipient.
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|
pubmed:affiliation |
EA 209-Eucaryotes Pathogènes: Transports Membranaires et Chimiorésistance, Université Paris Descartes, Paris, France.
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pubmed:publicationType |
Journal Article,
Case Reports
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