Linked Life Data

20037420

Source:http://linkedlifedata.com/resource/pubmed/id/20037420

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2009-12-28
pubmed:abstractText
We report a case of rapid growth GIST successfully treated with resection, which imatinib controlled it as a stable disease for three years. A 68-year-old woman underwent simple hysterectomy and bilateral oophorectomy for the pelvic tumor. In the operation, there were multiple disseminations in the greater omentum and peritoneum. After diagnosed as high risk GIST, the patient was treated with imatinib at a dose of 400 mg/day, and the tumor was controlled as a stable disease for 3 years. At the end of 2008, lower abdominal tumor grew rapidly and intra-abdominal hemorrhage appeared. Although sunitinib was administered at a dose of 37.5 mg/day, the tumor was enlarged, and sunitinib was stopped because the patient developed grade 3 diarrhea. IVR was tried to control abdominal hemorrhage, but it was unsuccessful. The patient's general condition was getting worse, ECOG performance status 3. In January 2009, the resection of main tumor was performed to control abdominal hemorrhage. After the operation, a general condition of the patient was getting better, ECOG performance status 1. The resection for drug resistant GIST may contribute to improve the patient's quality of life.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0385-0684
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2354-6
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
[A case of rapid growth GIST successfully treated with resection after long-term use of imatinib].
pubmed:affiliation
Department of Digestive Surgery, Yamaguchi University Graduate School of Medicine.
pubmed:publicationType
Journal Article, English Abstract, Case Reports