Linked Life Data

20036975

Source:http://linkedlifedata.com/resource/pubmed/id/20036975

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-12-28
pubmed:abstractText
Dilated cardiomypathies (DCM) are characterized by dilatation and pump dysfunction of the heart. DCM has an incidence of 6/100.000 people a year contributing to a considerable number of cases of heart failure. Although etiology and pathogenesis are known to be multifactorial, they remain mostly unidentified. Recent research identified patients affected with DCM with altered gene products. These alterations can roughly be grouped into causative genes, mostly coding for cytoskeletal proteins. Other genes seem to be activated after the disease onset and are able to influence the clinical course. In this study we systematically analyzed the role of genetic polymorphisms, based on peer-reviewed articles, published in scientific journals. A total of 97 original studies and a selected number of 60 genes, that seem to be related to DCM, have been reviewed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1945-0524
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
653-76
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Genetic polymorphisms in dilated cardiomyopathy.
pubmed:affiliation
Institute of Pathology, Medical University of Innsbruck, Muellerstrasse 44, A-6020 Innsbruck, Austria.
pubmed:publicationType
Journal Article, Review