Source:http://linkedlifedata.com/resource/pubmed/id/20035268
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2010-2-3
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pubmed:abstractText |
Neurochemical studies on the etiopathogenesis of depression are also focusing on the transduction system beyond receptors. Trimeric G-proteins play a crucial role in the transmembrane signalling, signal amplification and intracellular processing. Abnormalities of G-protein levels are observed in subjects with depression, G-protein modulation is considered to play a role in the antidepressant mode of action.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0172-780X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
592-8
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pubmed:meshHeading |
pubmed-meshheading:20035268-Animals,
pubmed-meshheading:20035268-Antidepressive Agents,
pubmed-meshheading:20035268-Cell Line, Tumor,
pubmed-meshheading:20035268-GTP-Binding Protein alpha Subunits,
pubmed-meshheading:20035268-Male,
pubmed-meshheading:20035268-Rats,
pubmed-meshheading:20035268-Rats, Wistar
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pubmed:year |
2009
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pubmed:articleTitle |
Acute and chronic effects of antidepressants on the G-protein alpha subunit profiles in vitro and in vivo.
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pubmed:affiliation |
1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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