Linked Life Data

20034843

Source:http://linkedlifedata.com/resource/pubmed/id/20034843

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-2-15
pubmed:abstractText
Francisella tularensis is a highly infectious Gram-negative bacterium causing the zoonotic disease tularemia. This facultative intracellular pathogen multiplies in vivo mainly inside macrophages, but has the capacity to infect and survive in many other cell types, including other phagocytic and nonphagocytic cells. In vitro, F. tularensis escapes rapidly from the phagosomal compartment and replicates in the cytoplasm of infected cells. An impressive number of novel genes related to F. tularensis pathogenesis have been identified recently. However, the information on biological functions still remains limited to a few of them. In this review, we will try to provide a comprehensive overview of the bacterial attributes, currently known-or suspected-to participate in F. tularensis virulence and will highlight the future challenges in F. tularensis research.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1879-0364
pubmed:author
pubmed:copyrightInfo
Copyright 2009 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11-7
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
The unraveling panoply of Francisella tularensis virulence attributes.
pubmed:affiliation
Université Paris Descartes, Faculté de Médecine Necker-Enfants Malades, Paris, France.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't