Linked Life Data

20034416

Source:http://linkedlifedata.com/resource/pubmed/id/20034416

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-12-25
pubmed:abstractText
The corpus luteum is formed from the pre-ovulatory follicle under the action of the mid-cycle LH surge. LH is the main luteotrophic hormone in women controlling luteal structure and function during the normal menstrual cycle. Local factors, however, including progesterone are also involved. If conception does not take place, luteolysis occurs as a physiological apoptotic process. Human chorionic gonadotrophin, secreted after implantation, is able to rescue the corpus luteum and extend its lifespan. In ovulation-induction cycles, the negative feedback effect of the ovarian steroids on the pituitary is markedly potentiated, leading to the suppression of endogenous LH secretion during the whole menstrual cycle. The marked suppression of LH secretion disrupts corpus luteum function regardless of the treatment regimen.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1472-6491
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
19 Suppl 4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4314
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Luteal-phase endocrinology.
pubmed:affiliation
Department of Obstetrics and Gynaecology, University of Thessalia, Medical School, 41110 Larissa, Greece. messinis@med.uth.gr
pubmed:publicationType
Journal Article