Source:http://linkedlifedata.com/resource/pubmed/id/20033691
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2010-6-4
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pubmed:abstractText |
The A(H5N1) influenza virus pandemic may be the result of avian H5N1 adapting to humans, leading to massive human to human transmission in a context of a lack of pre-existing immunity. As A(H1N1) and A(H5N1) share the same neuraminidase subtype, anti-N1 antibodies subsequent to H1N1 infections or vaccinations may confer some protection against A(H5N1). We analysed, by microneutralization assay, the A/Vietnam/1194/04 (H5N1) anti-N1 cross-protection acquired either during A/New-Caledonia/20/99 (H1N1) infection or vaccination. In cases with documented H1N1 infection, H5N1 cross-protection could be observed only in patients born between 1930 and 1950. No such protection was detected in the sera of vaccinated individuals.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1432-0991
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-8
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pubmed:meshHeading |
pubmed-meshheading:20033691-Adult,
pubmed-meshheading:20033691-Aged,
pubmed-meshheading:20033691-Aged, 80 and over,
pubmed-meshheading:20033691-Aging,
pubmed-meshheading:20033691-Antibodies, Neutralizing,
pubmed-meshheading:20033691-Antibodies, Viral,
pubmed-meshheading:20033691-Cross Protection,
pubmed-meshheading:20033691-Humans,
pubmed-meshheading:20033691-Influenza, Human,
pubmed-meshheading:20033691-Influenza A Virus, H1N1 Subtype,
pubmed-meshheading:20033691-Influenza A Virus, H5N1 Subtype,
pubmed-meshheading:20033691-Influenza Vaccines,
pubmed-meshheading:20033691-Middle Aged,
pubmed-meshheading:20033691-Neuraminidase,
pubmed-meshheading:20033691-Neutralization Tests,
pubmed-meshheading:20033691-Vaccination,
pubmed-meshheading:20033691-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Anti N1 cross-protecting antibodies against H5N1 detected in H1N1 infected people.
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pubmed:affiliation |
Laboratoire de Virologie, Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, 59 boulevard Pinel, 69677, Bron Cedex, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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