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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-3-22
pubmed:abstractText
The purpose of this study was to compare fasting and post-prandial glucose concentrations measured in venous blood with continuous glucose monitoring (CGM)-derived values, with and without prior exercise, in insulin-resistant, normoglycemic women. Interstitial and venous glucose concentrations were assessed in ten sedentary, overweight/obese African-American women following a sedentary condition (75 min of rest) and following an exercise condition (75 min of brisk walking on a treadmill). Ninety minutes after rest or exercise, participants completed an oral glucose tolerance test (OGTT). In response to the OGTT, CGM-derived glucose area under the curves (AUC) were lower than venous values in the exercise condition (-25%, p = 0.03) but this difference was attenuated in the sedentary condition (-10%, p = 0.09). Additionally, CGM-derived absolute glucose values (mMol) were significantly lower compared to venous values during the sedentary (p = 0.007) and exercise conditions (p = 0.006). Overall, there was a moderately strong relationship between venous and CGM-derived glucose AUC (r (2) = 0.68) but the CGM-derived values were consistently lower in this study group. Although CGM provided more information regarding post-prandial glucose responses, these results suggest that CGM may not closely match venous glucose measurements in normoglycemic participants.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1439-6327
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
108
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1181-7
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Use of continuous glucose monitoring in normoglycemic, insulin-resistant women.
pubmed:affiliation
Department of Kinesiology, University of Massachusetts, 106 Totman Building, Amherst, MA 01003, USA.
pubmed:publicationType
Journal Article