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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-1-20
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pubmed:abstractText |
Peripheral neuropathy and central nervous system neurodegeneration may result from the mitochondrial toxicity of some antiretroviral nucleoside analogues. We investigated whether this neuropathology may be antagonized by uridine supplementation in vivo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1473-5571
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
28
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
345-52
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pubmed:meshHeading |
pubmed-meshheading:20032772-Administration, Oral,
pubmed-meshheading:20032772-Animals,
pubmed-meshheading:20032772-Anti-HIV Agents,
pubmed-meshheading:20032772-DNA, Mitochondrial,
pubmed-meshheading:20032772-Drug Interactions,
pubmed-meshheading:20032772-Lipid Peroxidation,
pubmed-meshheading:20032772-Male,
pubmed-meshheading:20032772-Mice,
pubmed-meshheading:20032772-Mice, Inbred BALB C,
pubmed-meshheading:20032772-Mitochondrial Encephalomyopathies,
pubmed-meshheading:20032772-Mitochondrial Myopathies,
pubmed-meshheading:20032772-Uridine,
pubmed-meshheading:20032772-Zalcitabine,
pubmed-meshheading:20032772-Zidovudine
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pubmed:year |
2010
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pubmed:articleTitle |
Oral uridine supplementation antagonizes the peripheral neuropathy and encephalopathy induced by antiretroviral nucleoside analogues.
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pubmed:affiliation |
Department of Rheumatology and Clinical Immunology, Medizinische Universitätsklinik, Freiburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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