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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-12-24
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pubmed:abstractText |
A 10% cumulative incidence and a 0.3% per year incidence rate of sudden cardiac death in patients younger than 40 years and without therapy have been reported in type 1 long-QT syndrome. The Y111C-KCNQ1 mutation causes a severe phenotype in vitro, suggesting a high-risk mutation. This study investigated the phenotype among Y111C-KCNQ1 mutation carriers in the Swedish population with a focus on life-threatening cardiac events.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1942-3268
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
558-64
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pubmed:meshHeading |
pubmed-meshheading:20031635-Adolescent,
pubmed-meshheading:20031635-Adult,
pubmed-meshheading:20031635-Aged,
pubmed-meshheading:20031635-Child,
pubmed-meshheading:20031635-Child, Preschool,
pubmed-meshheading:20031635-Death, Sudden, Cardiac,
pubmed-meshheading:20031635-Female,
pubmed-meshheading:20031635-Follow-Up Studies,
pubmed-meshheading:20031635-Humans,
pubmed-meshheading:20031635-Incidence,
pubmed-meshheading:20031635-KCNQ1 Potassium Channel,
pubmed-meshheading:20031635-Male,
pubmed-meshheading:20031635-Middle Aged,
pubmed-meshheading:20031635-Mutation, Missense,
pubmed-meshheading:20031635-Pedigree,
pubmed-meshheading:20031635-Romano-Ward Syndrome,
pubmed-meshheading:20031635-Sweden,
pubmed-meshheading:20031635-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Low incidence of sudden cardiac death in a Swedish Y111C type 1 long-QT syndrome population.
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pubmed:affiliation |
Division of Pediatrics, Department of Clinical Sciences, Cardiology Heart Centre, Umeå University Hospital, Umeå, Sweden. annika.winbo@pediatri.umu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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