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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-12-24
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pubmed:abstractText |
The upstream transcription factor 1 (USF1) gene is associated with familial combined hyperlipidemia, the most common genetic dyslipidemia in humans, as well as with various dyslipidemic changes in numerous other studies. Typical of complex disease-associated genes, neither the explicit mutations have been described nor the functional consequences for risk allele carriers been reported at the cellular or tissue level.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1942-3268
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
522-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20031629-Adipose Tissue,
pubmed-meshheading:20031629-Adult,
pubmed-meshheading:20031629-Aged,
pubmed-meshheading:20031629-Cohort Studies,
pubmed-meshheading:20031629-Dyslipidemias,
pubmed-meshheading:20031629-Fats,
pubmed-meshheading:20031629-Female,
pubmed-meshheading:20031629-Gene Expression,
pubmed-meshheading:20031629-Humans,
pubmed-meshheading:20031629-Insulin,
pubmed-meshheading:20031629-Middle Aged,
pubmed-meshheading:20031629-Muscles,
pubmed-meshheading:20031629-Polymorphism, Single Nucleotide,
pubmed-meshheading:20031629-Twins,
pubmed-meshheading:20031629-Up-Regulation,
pubmed-meshheading:20031629-Upstream Stimulatory Factors
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pubmed:year |
2009
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pubmed:articleTitle |
Functional variant disrupts insulin induction of USF1: mechanism for USF1-associated dyslipidemias.
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pubmed:affiliation |
Institute for Molecular Medicine Finland (FIMM), National Institute for Health and Welfare, University of Helsinki, Helsinki, Finland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Twin Study
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