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pubmed:abstractText |
Previous studies indicate that the endothelin system is involved in hypertension, heart failure, atherosclerosis, chronic kidney disease, and diabetes. To explore the potential genetic effects of copy number variations (CNVs) on the endothelin system, which underlie these diseases, we studied the association of genome-wide CNVs with gene expression levels of 7 genes involved in the endothelin system using independent HapMap subjects including 90 Asians (45 Han Chinese and 45 Japanese), 60 whites, and 60 blacks.
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pubmed:affiliation |
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Mich 48109, USA. yansun@umich.edu
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