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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-12-24
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pubmed:abstractText |
Brain arteriovenous malformations (BAVMs) are a tangle of abnormal vessels directly shunting blood from the arterial to venous circulation and an important cause of intracranial hemorrhage (ICH). EphB4 is involved in arterial-venous determination during embryogenesis; altered signaling could lead to vascular instability resulting in ICH. We investigated the association of single-nucleotide polymorphisms (SNPs) and haplotypes in EPHB4 with risk of ICH at clinical presentation in patients with BAVM.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1942-3268
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
476-82
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pubmed:dateRevised |
2011-8-23
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pubmed:meshHeading |
pubmed-meshheading:20031623-Adult,
pubmed-meshheading:20031623-Cohort Studies,
pubmed-meshheading:20031623-Cross-Sectional Studies,
pubmed-meshheading:20031623-Female,
pubmed-meshheading:20031623-Haplotypes,
pubmed-meshheading:20031623-Humans,
pubmed-meshheading:20031623-Intracranial Arteriovenous Malformations,
pubmed-meshheading:20031623-Intracranial Hemorrhages,
pubmed-meshheading:20031623-Male,
pubmed-meshheading:20031623-Middle Aged,
pubmed-meshheading:20031623-Polymorphism, Single Nucleotide,
pubmed-meshheading:20031623-Receptor, EphB4,
pubmed-meshheading:20031623-Risk Factors
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pubmed:year |
2009
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pubmed:articleTitle |
EPHB4 gene polymorphisms and risk of intracranial hemorrhage in patients with brain arteriovenous malformations.
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pubmed:affiliation |
Center for Cerebrovascular Research, University of California, San Francisco, Calif 94110, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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