Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-11-2
pubmed:abstractText
Oncological emergencies are common conditions associated with significant morbidity and mortality. Delay in diagnosis and treatment can result in unfavourable outcomes. Cancer itself, cancer-related hormones or cytokines, or treatment effects can cause emergency problems. Febrile neutropaenia, frequently associated with chemotherapy, can lead to life-threatening conditions. Treatment requires systematic evaluation and early empirical antibiotics. Hypercalcaemia of malignancy is the most common metabolic emergency in cancer patients. Non-specific clinical features may cause delay in diagnosis and increase morbidity and mortality. Treatment includes active fluid resuscitation, diuretics and intravenous bisphosphonates. Superior vena cava syndrome is usually caused by external compression. Computerised tomography is useful to confirm diagnosis, evaluate the extent of disease and guide invasive tissue diagnosis. Treatment and prognosis depend on the underlying malignancies. Spinal cord compression is a true emergency due to risk of permanent neurological impairment. Localised back pain is the most common presenting symptom while late presentation of neurological deficit is associated with irreversible outcomes. Magnetic resonance imaging is the investigation of choice. Treatment includes corticosteroids, radiotherapy and/or decompressive surgery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
N
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1365-2354
pubmed:author
pubmed:copyrightInfo
© 2009 The Authors. European Journal of Cancer Care © 2009 Blackwell Publishing Ltd.
pubmed:issnType
Electronic
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
707-13
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Oncological emergencies: clinical importance and principles of management.
pubmed:affiliation
Research and Development Department, Lincoln County Hospital, Lincoln, UK. ssamphao@hotmail.com
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't