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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-5-26
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pubmed:abstractText |
Alopecia areata (AA) is a common hair loss disorder with a complex mode of inheritance. Autoimmune mechanisms are presumed to be crucial aetiologically. It is plausible that a number of autoimmune disorders may share a common genetic background. This phenomenon has been demonstrated in previous studies, which have shown an overlap of susceptibility alleles between AA and other autoimmune disorders. Recent studies have shown that genetic variants on the TRAF1/C5 (tumor necrosis factor receptor-associated factor 1, complement component 5) locus confer susceptibility to rheumatoid arthritis (RA).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1365-2133
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pubmed:author |
pubmed-author:BöhmMM,
pubmed-author:BeckerTT,
pubmed-author:BetzR CRC,
pubmed-author:BlaumeiserBB,
pubmed-author:BrockschmidtF FFF,
pubmed-author:De WeertJJ,
pubmed-author:EigelshovenSS,
pubmed-author:ForstbauerLL,
pubmed-author:GiehlK AKA,
pubmed-author:HannekenSS,
pubmed-author:HeroldCC,
pubmed-author:LVOVAT NTN,
pubmed-author:LutzGG,
pubmed-author:NöthenM MMM,
pubmed-author:RedlerSS,
pubmed-author:WolffHH
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pubmed:issnType |
Electronic
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pubmed:volume |
162
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
866-9
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pubmed:meshHeading |
pubmed-meshheading:20030635-Adolescent,
pubmed-meshheading:20030635-Adult,
pubmed-meshheading:20030635-Aged,
pubmed-meshheading:20030635-Aged, 80 and over,
pubmed-meshheading:20030635-Alopecia Areata,
pubmed-meshheading:20030635-Case-Control Studies,
pubmed-meshheading:20030635-Child,
pubmed-meshheading:20030635-Child, Preschool,
pubmed-meshheading:20030635-Chromosome Mapping,
pubmed-meshheading:20030635-Complement C5,
pubmed-meshheading:20030635-Female,
pubmed-meshheading:20030635-Genetic Markers,
pubmed-meshheading:20030635-Genetic Predisposition to Disease,
pubmed-meshheading:20030635-Humans,
pubmed-meshheading:20030635-Male,
pubmed-meshheading:20030635-Middle Aged,
pubmed-meshheading:20030635-Pedigree,
pubmed-meshheading:20030635-Polymorphism, Single Nucleotide,
pubmed-meshheading:20030635-Risk Factors,
pubmed-meshheading:20030635-Severity of Illness Index,
pubmed-meshheading:20030635-TNF Receptor-Associated Factor 1,
pubmed-meshheading:20030635-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
The TRAF1/C5 locus confers risk for familial and severe alopecia areata.
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pubmed:affiliation |
Institute of Human Genetics, University of Bonn, Sigmund-Freud-Str. 25, D-53127, Bonn, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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