Linked Life Data

20030556

Source:http://linkedlifedata.com/resource/pubmed/id/20030556

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-1-11
pubmed:abstractText
The most commonly used regulatory T cell (Treg) phenotypes, CD4(+)CD25(hi)CD127(lo) and CD4(+)CD25(hi)FoxP3(+), were simultaneously used to determine the Treg frequency in 2 different groups of human immunodeficiency virus (HIV)-infected persons, one viremic and other aviremic. As expected, a strong correlation between both Treg phenotypes was observed in the aviremic group (r = 0.913; P < .001), but surprisingly, this correlation was completely absent in the viremic group (r = 0.143; P = .572). Data on T cell activation levels of both HIV groups suggest that the CD4(+)CD25(hi)CD127(lo) phenotype could just be mirroring the elevated numbers of activated non-regulatory T cells in the viremic HIV group.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1537-6613
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
201
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
331-5
pubmed:dateRevised
2010-3-13
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
CD4(+)CD25(+/hi)CD127(lo) phenotype does not accurately identify regulatory T cells in all populations of HIV-infected persons.
pubmed:affiliation
Immunovirology Laboratory, Infectious Diseases Service, Institute of Biomedicine of Seville, Virgen del Rocío Universitary Hospital, Seville, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't